Residues of Ceftiofur Sodium in Rabbit Tissues

A Review on Ceftiofur Sodium

Ceftiofur is third generation cephalosporin, broad spectrum antibiotic. It inhibits the cell wall synthesis of bacteria. Ceftiofur is widely used in animals for the treatment of various diseases. Ceftiofur is used against Gram positive and Gram negative bacteria. It has been approved world widely for the treatment of respiratory diseases in sheep, goats, cattle and horses. Ceftiofur sodium phar...

Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions

Stability of ceftiofur sodium and cefquinome sulphate in intravenous solutions was studied. Chromatographic separation and quantitative determination were performed by using a high-performance liquid chromatography with UV-DAD detection. During the stability study, poly(vinylchloride) minibags were filled with a solution containing 5 mg of ceftiofur sodium or cefquinome sulphate and diluted to ...

Pharmacokinetics of ceftiofur sodium in exotic and domestic avian species.

The pharmacokinetics of ceftiofur sodium were determined in domestic chicks, turkey poults, adult cockatiels (Nymphicus hollandicus), and adult orange-winged Amazon parrots (Amazona amazonica) after subcutaneous (chicks and turkey poults and intramuscular (i.m.) dosing (cockatiels and Amazon parrots). Turkey poult data were best fit to a single exponential model with disappearance half-lives (t...

Drug residues in animal tissues.

Pulmonary pharmacokinetics of desfuroylceftiofur acetamide after nebulisation or intramuscular administration of ceftiofur sodium to weanling foals.

REASONS FOR PERFORMING STUDY Administration of ceftiofur sodium via nebulisation has been recommended for the treatment of bronchopneumonia in horses, despite the lack of pharmacokinetic and safety data. OBJECTIVES To compare concentrations of desfuroylceftiofur acetamide (DCA) in plasma and pulmonary epithelial lining fluid (PELF) of foals after nebulisation or i.m. administration of ceftiof...